This Sunday featured eleven 100+ yard rushers. Not all of them grabbed a touchdown, but all were worth plenty of points in most standard leagues. Let's take a look at their stats.
Name (Team): Carries - Yards - Yards per carry - Touchdown(s)
Adrian Peterson (MIN): 18 - 133 - 7.4 - 2
Chris Johnson (TEN): 26 - 132 - 5.1 - 2
Steven Jackson (STL): 26 - 131 - 5.0 - 1
Justin Forsett (SEA): 17 - 123 - 7.2 - 1
Maurice Jones-Drew (JAC): 24 - 123 - 5.1 - 1
Michael Bush (OAK): 14 - 119 - 8.5 - 0
Ladell Betts (WAS): 26 - 114 - 4.4 - 1
Michael Turner (ATL): 9 - 111 - 12.3 - 0
Frank Gore (SF): 25 - 104 - 4.2 - 1
Jamaal Charles (KC): 18 - 103 - 5.7 - 1
Ricky Williams (MIA): 20 - 102 - 5.1 - 0
At least half of the above running backs should be started by 80% of teams. Every week there are surprises and players that will be swept up off the waiver wire. Some you should avoid, some are worthwhile. From the above, take a good hard look at Jamaal Charles and a lighter look at Justin Forsett. Julius Jones left the game with an injury, leaving Forsett to very ably fill in for him. Against the tough Arizona run defense, Forsett excelled and there may be some turnover for the Seahawks in the backfield, but Jamaal Charles should have solidified his starting role this week. There will be a couple duds going forward, but he's a worthwhile flex option in most leagues.
Always start a few of the above; namely Adrian Peterson, Chris Johnson, Maurice Jones-Drew and Michael Turner. They will rarely disappoint you.